Keynote Speakers

The Organising Committee of ISCAS 2014 is pleased to announce 2014 Keynote Speakers.

Don_Ingber Professor Donald E. Ingber
Date: Monday 2 June 2014
Time: 0910 – 1010
Room: Plenary 3
Microengineered Human Organs On Chips

Donald E. Ingber, M.D.,Ph.D.
Director, Wyss Institute for Biologically Inspired Engineering at Harvard University, Judah Folkman Professor of Vascular Biology, Harvard Medical School & Boston Children’s Hospital, and Professor of Bioengineering, Harvard School of Engineering & Applied Sciences

In this presentation, I will describe work we have been carrying out in the Biomimetic Microsystems platform at the Wyss Institute for Biologically Inspired Engineering at Harvard. The goal of this platform is to engineer human ‘Organs-on-Chips’: microchips containing hollow microfluidic channels lined by living human cells created with microfabrication techniques that recapitulate organ-level functions as a way to replace animal testing for drug development and to create in vitro human disease models. I will review recent advances we have made in development of multiple organ chips, including human lung, gut, kidney, liver and bone marrow chips, as well as a human disease models-on-chips that mimic pulmonary edema and inflammatory bowel disease. In addition, I will describe our ongoing efforts to develop more than 10 different organ chips, to integrate them into a ‘human body on chips’, and to engineer an automated instrument for real-time analysis of cellular responses to pharmaceuticals, toxins and other chemicals.

Stephan Skilkerich Dr. Stephan C. Stilkerich
Date: Tuesday 3 June 2014
Time: 0940 – 1040
Room: Plenary 3
Model Based Engineering of Highly Mobile Systems of Systems: Safe Aeroplanes; Safer Automobiles

Stephan C. Stilkerich

Expert, Airbus Group Innovation

In the aerospace and automotive industries world-wide, electronic systems and their software are required to perform real-time control that is critical for the safe operation of airplanes and cars, including while operating in dense traffic and simultaneously reducing the environmental impact. Indeed, these enormously complex safety critical systems are already deployed pervasively as networks of tens to hundreds of interacting real-time controllers not only in transportation but also in the energy, infrastructure, and medical industries. Every system classified and regulated as safety critical, throughout the developed world, undergoes rigorous development and verification prior to being certified by the regulating authorities and approved for use – particularly so in aerospace, nuclear power and medicine but, unfortunately, less so in automotive and infrastructure.This key note will describe the constraints, development and certification of safety critical systems, primarily, in the aerospace industry. Two regulations that are of central relevance in the aerospace domain will inform this talk, (i) the software centric “Software Considerations in Airborne Systems and Equipment Certification” (DO-178) and the hardware centric “Design Assurance Guidance for Airborne Electronic Hardware” (DO-254). The presentation will discuss aspects of aerospace engineering, as diverse as the use of formal and empirical verification software and hardware and the prospects for multicore processors in safe real-time control. Dr. Stilkerich, who is a practicing aerospace engineer, provides a unique insight into the safety concerns and practices of the aerospace industry from his point of view.

In the final section following the body of the Keynote, we will engage in a discussion and comparison of the engineering practices in the aerospace and automotive industries – including the status of the confirmed ISO26262 automotive standard on automotive functional safety. A question of particular interest will be, why a million deaths annually in automobile crashes has, to date, had such little impact on the economics and safety of automotive engineering.

Victor pic Professor Victor Zhirnov
Date: Tuesday 3 June 2014
Time: 1400 – 1500
Room: Plenary 3
Scaling limits of nanoionic devices

Victor Zhirnov
Director, Special Projects at the Semiconductor Research Corporation

Device scaling and energy consumption during computation has become a matter of strategic importance for modern Information and Communication Technologies (ICT). The central question addressed in this talk is: What is the smallest volume of matter needed for ICT devices, such as memory or logic? The scaling limits of electron-based devices, such as transistors are~5-7 nm due to quantum-mechanical tunneling. Smaller devices can be made, if information-bearing particles are used whose mass is greater than the mass of an electron. Therefore the new principles for ICT devices, scalable to ~1 nm, could be ‘moving atoms’ instead of ‘moving electrons’, for example using nanoinonic structures.

An important task for sub-10 nm nanodevices is recognition of the fundamental role of ‘defects’ that should not be treated as imperfections but instead as controllable entities. The materials nonstoichiometry due to point defects plays a key role in the electronic properties of many materials, for example in metal oxides. Due to these nonstoichiometric defects, the materials often behave as doped semiconductors. In fact, these materials form a special class, sometimes called ‘chemiconductors’.

The nanoionic resistive switching devices may offer a promising path to replace the foundation of today’s computing technologies. Examples include memory (ReRAM) and logic (atomic/ionic switches). A related concept, the memristor, is currently being actively explored for different information processing tasks. As will be discussed in this presentation, biological computation is extensively based on heavy particles to represent and process information. Based on the biological computing analogy, future ‘neuromorphic’ computational architectures could be implemented by using nanoionic devices.

Iven Mareels pic Professor Iven Mareels
Date: Wednesday 4 June 2014
Time: 1400 – 1500
Room: Plenary 3
Circuits and Systems for Modern Irrigation Management

Iven Mareels

Dean, School of Engineering, University of Melbourne

Irrigation, water for food, accounts for nearly 70% of the world’s fresh water use. 70% of all irrigation water is distributed through large open channel systems, most of which are even today operated on principles that have not changed much since the Sumerians built their civilisation in Mesopotamia about 3,000BC on the basis of irrigated agriculture.

Water efficiency (water used for the purpose it was extracted from the environment as a fraction of the amount extracted from the environment) is typically less than 50% on average (rural, domestic or industrial use). Moreover, it is estimated that fresh water use is already well above sustainable levels, and is under pressure from population growth, climate change, as well as economic equity demands.

Adaptation of the irrigation infrastructure and water management practices is therefore essential to support the expected population growth in a sustainable manner. Urgent action is advocated by such diverse groups as the 2030 Water Resources Group, the World Bank, the UNESCO, as well as the US Department of Defence.

Australia is well known for its extremes of extended droughts alternated by periods of floods. Water management in the face of climate change, population growth and environmental protection is therefore an ever pressing socio-economic issue and Australia is therefore as an ideal place to implement and test novel water management practices.

From a systems engineering point of view, water management requires information, and an ability to implement decision. Obtaining good information and implementing the right decisions are however hard to do because of the diversity of time and spatial scales involved in the irrigation system (more than 10 orders of magnitude).

In this lecture, we present an overview of nearly 15 years of research, development and commercialisation of novel water management systems by the University of Melbourne (in collaboration with a number of research organisations) and Rubicon Water. This collaboration has led to a smart water management system an internet of things dedicated to irrigation water management. The focus in this lecture is primarily on the circuits and the systems that underpin this internet of things for water management. Some of the circuits that are required to determine water levels and water flows in channels, to closing the loop from thirsty plants to water release from a dam will be presented. A systems engineering approach will be adhered to throughout the lecture. Future plans will be discussed, as well as some of the challenges.